Imaging permits 3D depiction of anatomy ranging from macro- and meso- to micro-morphology along with quantitative parametric mapping of tissue properties. This includes the visualization and quantitative characterization of organ, tissue, cellular and molecular function.
Our team develops, tests, and applies imaging methods for both preclinical and clinical applications. We are particularly interested in translation of preclinical imaging methods for small animals to clinical applications in humans.
For preclinical imaging all relevant imaging modalities are available "under one roof" in the Molecular Imaging North Competence Center (MOIN CC). This includes magnetic resonance, x-ray computed tomography, fluorescence, bioluminescence, sonographic and photoacoustic approaches.
The corresponding clinical imaging devices are available in the Department of Diagnostic and Neuroradiology. Among quantitative clinical imaging methods, the Section focused on High Resolution Quantitative Computed Tomography and Quantitative Ultrasound approaches of musculoskeletal disorders.
For parametric analysis of both preclinical or clinical image data image processing tools, including in-house software packages for quantitative image analyses, have been developed by the Section.
Imaging methods permit to investigate a very broad range of disease areas. Our team has in depth experience in oncology, neuroscience and the musculoskeletal system.
Imaging is not limited to diagnostic or prognostic objectives but includes therapeutic applications. Theranostic applications combine diagnosis and therapy. For example drugs can be labeled to monitor their distribution in the body and their accumulation in target organs. Drugs can be encapsulated in nanoparticles for improved drug delivery, release and action, an approach referred to as nanotheranostics, and again these nanocarriers can be labeled to monitor drug delivery and release along with organ response.